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## Top 5 Hot Stocks on Nasdaq for May 15, 2025

Based on market performance, analyst ratings, and news from May 15, 2025, the following five Nasdaq-listed stocks stood out as especially hot for the day:

**1. Exelixis, Inc. (EXEL)**
– Shares of Exelixis surged 20.1% after the company reported first-quarter 2025 earnings of $0.62 per share, significantly beating expectations[4].

**2. Cisco Systems Inc. (CSCO)**
– Cisco was one of the top performing Nasdaq 100 stocks, gaining +4.9% on the day[3].

**3. Xcel Energy Inc. (XEL)**
– Xcel Energy rose +3.1%, ranking among the top gainers on the Nasdaq 100[3].

**4. Vertex Pharmaceuticals Inc. (VRTX)**
– Vertex Pharmaceuticals also performed strongly, up +3.0%[3].

**5. Amgen Inc. (AMGN)**
– Amgen gained +3.0%, rounding out the top five for Nasdaq 100 performers[3].

### Honorable Mentions and Other Notables

– **AI-related stocks** like Nvidia (NVDA), Palantir (PLTR), and Advanced Micro Devices (AMD) remained in the spotlight due to investor interest and recent rallies, although they were not necessarily the biggest single-day gainers[1].
– **Super Micro Computer (SMCI)** saw exceptional performance earlier in the week with shares soaring about 40%, but specific daily data for May 15 is not provided[1].

### Summary Table

| Stock Ticker | Company Name | Performance (May 15, 2025) | Notes |
|————–|————————-|——————————|——————————-|
| EXEL | Exelixis, Inc. | +20.1% | Strong earnings beat |
| CSCO | Cisco Systems Inc. | +4.9% | Top Nasdaq 100 performer |
| XEL | Xcel Energy Inc. | +3.1% | Top Nasdaq 100 performer |
| VRTX | Vertex Pharmaceuticals | +3.0% | Top Nasdaq 100 performer |
| AMGN | Amgen Inc. | +3.0% | Top Nasdaq 100 performer |

These five stocks were among the hottest on the Nasdaq for May 15, 2025, based on their strong price performance and/or notable news catalysts[3][4].

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